ERK-dependent DICER1 phosphorylation promotes open chromatin state and lineage plasticity to mediate tumor progression
R. A. Reyes-Castro, S.-Y. Chen, J. Seemann, S. Arur
The paper shows that phosphorylated DICER1 promotes open chromatin and lineage plasticity in lung adenocarcinomas, independent of miRNAs and EMT.
bioRxiv · Nov 1, 2022 · PreprintCancer Biology