Author

S. B. Jadhav

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Cancer Biology· 1

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:metabolomics· 1 Assay:proteomics· 1

Frequent Co-Authors

C. Sandoval Acuna· 1 shared J. Stursa· 1 shared J. Truksa· 1 shared K. Blazkova· 1 shared K. Klanicova· 1 shared L. Werner· 1 shared R. Sedlacek· 1 shared Y. Pacior Pampin· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperCancer Biology

C. Sandoval Acuna

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1 paper

Recent·Most cited

Selective killing of cancer cells via simultaneous destabilization of mitochondrial iron metabolism and induction of ferroptosis elicited by mitochondrially targeted iron chelator deferasirox

S. B. Jadhav, C. Sandoval Acuna, Y. Pacior Pampin, K. Klanicova, K. Blazkova, R. Sedlacek, J. Stursa, L. Werner, J. Truksa

This study introduces mitoDFX, a mitochondrially targeted iron chelator that simultaneously depletes iron and induces ferroptosis, showing high selectivity and efficacy against cancer cells.

bioRxiv · Jan 17, 2024 · PreprintCancer Biology