S. Barber-Zucker

Designed high-redox potential laccases exhibit high functional diversity

The paper designs high-redox potential laccases with improved stability and functional diversity through stabilization and active-site engineering.

Stable and functionally diverse versatile peroxidases by computational design directly from sequence

The paper designs stable and functionally diverse versatile peroxidases using computational methods, showing improved expression and environmental tolerance compared to wild-type enzymes.

The metal binding site composition of the cation diffusion facilitator protein MamM cytoplasmic domain impacts its metal responsivity

This study investigates how mutations in the metal binding sites of the MamM CTD affect its conformation and metal binding properties using X-ray crystallography and Trp-fluorescence spectrometry.

The cation diffusion facilitator protein MamM's cytoplasmic domain exhibits metal-type dependent binding modes and discriminates against Mn2+

This study investigates how the cytoplasmic domain of the CDF protein MamM binds different metals, showing it discriminates against Mn2+ and supports a role for CTDs in metal selectivity.

Transition metal binding selectivity in proteins and its correlation with the phylogenomic classification of the cation diffusion facilitator protein family

The paper analyzes DDMC binding propensities and correlates them with the phylogenetic classification of the CDF protein family to understand metal selectivity in transporters.