Author

S. Bekiranov

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cancer Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:ChIP-seq· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:drug response / drug discovery· 2 Organism:yeast· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

D. T. Auble· 2 shared E. A. Hoffman· 2 shared S. J. Shetty· 2 shared A. Salamon· 1 shared B. Kull· 1 shared C. Lehman· 1 shared D. Gioeli· 1 shared E. Petricoin· 1 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersBiochemistry

D. T. Auble

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Mouse Model of Heart Attack and Stroke Shows Improved Survival with MPO Inhibition

S. Shamsuzzaman, R. A. Deaton, H. Doviak, M. Evans, A. Salamon, S. Karnewar, V. Serbulea, G. F. Alencar, L. S. Shankman, K. Walsh, S. Bekiranov, O. Kocher, M. Kreiger, B. Kull, M. Persson, , G. K. Owens

The paper introduces a mouse model of advanced atherosclerosis that exhibits spontaneous plaque rupture leading to MI or stroke, and shows that MPO inhibition with AZM198 reduces mortality and plaque rupture incidence.

Circulation · Aug 27, 2024Peer-reviewedPhysiology

Genome-scale chromatin interaction dynamic measurements for key components of the RNA Pol II general transcription machinery

K. Kupkova, S. J. Shetty, E. A. Hoffman, S. Bekiranov, D. T. Auble

The paper measures genome-scale chromatin interaction dynamics of RNA Pol II GTFs in budding yeast, revealing kinetic patterns linked to gene function and transcription rates.

bioRxiv · Jul 25, 2023Biochemistry

The potentiative cytotoxic effect of IGF1R and EGFR inhibition on the Head and Neck Cancer Proteome

S. Hall, C. Lehman, J. Wulfkuhle, E. Petricoin, S. Bekiranov, S. Dolatshahi, M. Jameson, D. Gioeli

This study investigates the combined effect of IGF1R and EGFR inhibitors on HNSCC proteome, showing enhanced inhibition of receptor tyrosine kinase signaling through pathway analysis.

bioRxiv · Oct 13, 2022 · PreprintCancer Biology

Second-generation method for analysis of chromatin binding using formaldehyde crosslinking kinetics

H. Zaidi, E. A. Hoffman, S. J. Shetty, S. Bekiranov, D. T. Auble

The paper improves the CLK method for analyzing chromatin binding kinetics by refining formaldehyde crosslinking conditions and revealing variability in crosslinking rates for different protein-DNA interactions.

bioRxiv · Jun 21, 2017Biochemistry