S. Bonifati

TRAF6 and TAK1 contribute to SAMHD1-mediated negative regulation of NF-kB signaling

This study identifies TRAF6 and TAK1 as mediators of SAMHD1's suppression of NF-κB activation and HIV-1 infection.

SAMHD1 Impairs HIV-1 Gene Expression and Reactivation of Viral Latency in CD4+ T-cells

This study shows that SAMHD1 suppresses HIV-1 gene expression and reactivation in CD4+ T-cells by binding to the HIV-1 LTR and inhibiting transcription.