Characterisation of the SARS-CoV-2 ExoN (nsp14ExoN-nsp10) complex: implications for its role in viral genome stability and inhibitor identification
H. T. Baddock, S. Brolih, Y. Yosaatmadja, M. Ratnaweera, M. Bielinski, L. Swift, A. Cruz-Migoni, G. M. Morris, C. J. Schofield, O. Gileadi, P. J. McHugh
This study characterizes the SARS-CoV-2 nsp14-nsp10 complex as an RNA nuclease, identifies its role in genome stability, and discovers inhibitors targeting this complex.
bioRxiv · Aug 13, 2020 · PreprintBiochemistry