Author

S. Brouns

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Assay:DNA methylation· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Approach:microscopy & imaging analysis· 2 Organism:bacteria (other)· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:comparative / phylogenetic analysis· 1

Frequent Co-Authors

A. Alassaf· 1 shared A. Asangba· 1 shared A. Cantu· 1 shared A. Cazares· 1 shared A. Kurilshikov· 1 shared A. Reyes· 1 shared A. Tyakht· 1 shared A. Vega· 1 shared

Activity by Year

2019-2019 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperMicrobiology

A. Alassaf

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Selective Prespacer Processing Ensures Precise CRISPR-Cas Adaptation

S. Kim, L. Loeff, S. Colombo, S. Brouns, C. Joo

This study identifies how Cas1-Cas2 selects and processes prespacers for CRISPR-Cas adaptation using single-molecule fluorescence and DnaQ exonucleases.

bioRxiv · Apr 16, 2019Biophysics

Direct visualization of native CRISPR target search in live bacteria reveals Cascade DNA surveillance mechanism

J. Vink, K. Martens, M. Vlot, R. McKenzie, C. Almendros, B. Estrada Bonilla, D. Brocken, J. Hohlbein, S. Brouns

The study visualizes Cascade complexes in live bacteria to reveal their DNA surveillance mechanism and how they detect invading DNA.

bioRxiv · Mar 25, 2019Microbiology

Global phylogeography and ancient evolution of the widespread human gut virus crAssphage

R. Edwards, A. Vega, H. Norman, M. C. Ohaeri, K. Levi, E. Dinsdale, O. Cinek, R. Aziz, K. McNair, J. Barr, K. Bibby, S. Brouns, A. Cazares, P. A. de Jonge, C. Desnues, , Doane

This study investigates the origin, evolution, and epidemiology of crAssphage, a widespread human gut virus, using global DNA sequences showing local phylogeographic clustering and ancient primate associations.

bioRxiv · Jan 26, 2019Microbiology