Author

S. Bruchmann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Evolutionary Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:bacteria (other)· 2 Research Focus:host-pathogen & immune response· 2 Assay:whole-genome sequencing· 2 Research Focus:chromatin & epigenetic regulation· 1 Approach:comparative / phylogenetic analysis· 1 Assay:DNA methylation· 1 Assay:metagenomics· 1

Frequent Co-Authors

A. J. Balmer· 2 shared A. S. M. M. Hossain· 2 shared A. W. Tucker· 2 shared J. Herbert· 2 shared L. A. Weinert· 2 shared M. Gottschalk· 2 shared M. Matuszewska· 2 shared A. A. van Belkum· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersEvolutionary Biology

A. J. Balmer

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

The emergence and diversification of a zoonotic pathogen from within the microbiota of intensively farmed pigs

G. G. R. Murray, A. S. M. M. Hossain, E. L. Miller, S. Bruchmann, A. J. Balmer, M. Matuszewska, J. Herbert, N. F. Hadjirin, R. Mugabi, G. Li, M. L. Ferrando, I. M. Fernades de Oliveira, T. Nguyen, P. L. K. Yen, H. D. Phuc, , L. A. Weinert

This study traces the emergence and spread of Streptococcus suis pathogens in pigs, linking their evolution to changes in farming practices and identifying genomic factors associated with pathogenicity.

bioRxiv · May 17, 2023Evolutionary Biology

Mutation rate dynamics reflect ecological change in an emerging zoonotic pathogen

G. Murray, A. J. Balmer, J. Herbert, N. F. Hadijirn, C. L. Kemp, M. Matuszewska, S. Bruchmann, A. S. M. M. Hossain, M. Gottschalk, A. W. Tucker, E. Miller, L. A. Weinert

The paper investigates how mutation rates in Streptococcus suis change with ecology and genome size, finding higher mutation rates in invasive disease isolates and a bias towards G/C to A/T mutations in more pathogenic strains.

bioRxiv · Apr 12, 2021Evolutionary Biology

Identifying virulence determinants of multidrug-resistant Klebsiella pneumoniae in Galleria mellonella

S. Bruchmann, T. Feltwell, J. Parkhill, F. Short

This study identifies virulence determinants of multidrug-resistant Klebsiella pneumoniae using Galleria mellonella infection model, highlighting surface polysaccharides and NfeR as key factors.

bioRxiv · Oct 30, 2020Microbiology

Mining zebrafish microbiota reveals key community-level resistance against fish pathogen infection

F. A. STRESSMANN, J. BERNAL-BAYARD, D. PEREZ-PASCUAL, B. AUDRAIN, O. RENDUELES, V. BRIOLAT, S. BRUCHMANN, S. VOLANT, A. GHOZLANE, S. HAUSSLER, E. DUCHAUD, J.-P. LEVRAUD, J.-M. GHIGO

The paper identifies key bacteria and community-level strategies that confer resistance to fish pathogen infection in zebrafish.

bioRxiv · Apr 23, 2020Microbiology

Discordant bioinformatic predictions of antimicrobial resistance from whole-genome sequencing data of bacterial isolates: An inter-laboratory study

R. M. Doyle, D. M. O'Sullivan, S. D. Aller, S. Bruchmann, T. G. Clark, A. Coello Pelegrin, M. Cormican, E. Diez Benavente, M. J. Ellington, E. McGrath, Y. Motro, T. Phuong Thuy Nguyen, J. Phelan, L. P. Shaw, R. A. Stabler, , K. A. Harris

This study evaluates the reproducibility of antimicrobial resistance predictions from whole-genome sequencing data across different laboratories and identifies factors contributing to discordant results.

Microbial Genomics · Feb 1, 2020Peer-reviewedMicrobiology