Monitoring extracellular ion and metabolite dynamics with recombinant nanobody-fused biosensors
S. Burgstaller, T. R. Wagner, H. Bischof, S. Bueckle, A. Padamsey, D. I. Frecot, P. D. Kaiser, D. Skrabak, R. Malli, R. Lukowski, U. Rothbauer
This study develops recombinant nanobody-fused biosensors to monitor extracellular K+, pH, and glucose in real time, demonstrating their utility in cancer and neuronal cells.
bioRxiv · Apr 12, 2022Biochemistry