Murine intrarectal instillation of purified recombinant C. difficile toxins enables mechanistic studies of pathogenesis
N. O. Markham, S. C. Bloch, J. A. Shupe, E. N. Laubacher, M. K. Washington, R. J. Coffey, D. B. Lacy
This study uses purified recombinant C. difficile toxins in a mouse model to investigate their pathogenic mechanisms and tissue effects.
bioRxiv · Aug 30, 2020Microbiology