Author

S. C. R. Lummis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:mechanistic / dynamical model· 2 Research Focus:protein folding & dynamics· 2 Organism:bacteria (other)· 1 Assay:cryo-EM· 1 Assay:electrophysiology· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. J. Pedersen· 1 shared A. Mehregan· 1 shared A. S. Kristensen· 1 shared A. Sridhar· 1 shared B. Bang-Andersen· 1 shared B. Schiott· 1 shared C. C. Brun· 1 shared C. Chipot· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiochemistry

A. J. Pedersen

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Structural Determinants for Activity of the Antidepressant Vortioxetine at Human and Rodent 5-HT3 receptors

U. Lopez-Sanchez, L. J. Munro, L. K. Ladefoged, A. J. Pedersen, C. C. Brun, S. M. Lyngby, D. Baud, M. G. Pedersen, S. C. R. Lummis, B. Bang-Andersen, B. Schiott, C. Chipot, G. Schoehn, J. Neyton, F. Dehez, , A. S. Kristensen

This study investigates how vortioxetine interacts with human and rodent 5-HT3 receptors, revealing structural differences and mechanisms of action.

bioRxiv · Feb 23, 2024 · PreprintBiochemistry

A cationic lipid site at the outward transmembrane face of a pentameric ligand-gated ion channel

A. Sridhar, S. C. R. Lummis, D. Pasini, A. Mehregan, M. Brams, K. Kambara, D. Bertrand, E. Lindahl, R. J. Howard, C. Ulens

This study identifies a cationic lipid binding site on the outward face of the ELIC pLGIC, supported by simulations and mutagenesis, with implications for lipid modulation and drug design.

bioRxiv · Mar 24, 2021 · PreprintBiophysics