Nascent adhesions differentially regulate lamellipodium velocity and persistence
K. R. Carney, A. M. Khan, S. C. Samson, N. Mittal, S. J. Han, M. C. Mendoza, T. C. Bidone
The paper develops a computational model to study how actin and adhesions regulate cell migration, finding that actin polymerization drives protrusion while adhesion lifetime affects velocity and persistence.
bioRxiv · Nov 15, 2021 · PreprintCell Biology