Author

S. C. Sealfon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Research Focus:differential expression· 3 Approach:statistical model· 3 Approach:deep learning· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Organism:mouse· 2 Assay:scRNA-seq· 2

Frequent Co-Authors

G. R. Smith· 3 shared O. G. Troyanskaya· 3 shared D. J. Bernard· 2 shared F. M. Ruf-Zamojski· 2 shared J. L. Turgeon· 2 shared M. A. S. Amper· 2 shared M. Zamojski· 2 shared N. Mendelev· 2 shared

Activity by Year

2020-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCell Biology

G. R. Smith

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

CHARM: COVID-19 Health Action Response for Marines - association of antigen-specific interferon-gamma and IL2 responses with asymptomatic and symptomatic infections after a positive qPCR SARS-CoV-2 test

M. Sedegah, C. Porter, M. R. Hollingdale, H. Ganeshan, J. Huang, C. W. Goforth, M. Belmonte, A. Belmonte, D. L. Weir, R. A. Lizewski, S. E. Lizewski, S. C. Sealfon, V. Jani, Y. Cheng, S. Inoue, , A. Letizia

CHARM study examines T cell responses in asymptomatic and symptomatic SARS-CoV-2 infected Marines, finding persistent IFN-gamma responses to S, N, and M proteins, with higher frequencies to N in asymptomatic cases.

bioRxiv · Dec 13, 2021Immunology

Single nucleus pituitary transcriptomic and epigenetic landscape reveals human stem cell heterogeneity with diverse regulatory mechanisms

Z. Zhang, M. Zamojski, G. R. Smith, T. L. Willis, V. Yianni, N. Mendelev, H. Pincase, N. Seenarine, M. A. S. Amper, M. Vasoya, V. Nair, J. L. Turgeon, D. J. Bernard, O. G. Troyanskaya, C. L. Andoniadou, , F. M. Ruf-Zamojski

The paper characterizes human pituitary stem cells using single nucleus RNA-seq and ATAC-seq, revealing distinct cell types, regulatory mechanisms, and age-related differences.

bioRxiv · Jun 18, 2021 · PreprintCell Biology

mRNA-1273 efficacy in a severe COVID-19 model: attenuated activation of pulmonary immune cells after challenge

M. Meyer, Y. Wang, D. Edwards, G. R. Smith, A. B. Rubenstein, P. Ramanathan, C. E. Mire, C. Pietzsch, X. Chen, Y. Ge, W. S. Cheng, C. Henry, A. Woods, L. Ma, G. B. E. Stewart-Jones, , A. Bukreyev

This study evaluates mRNA-1273 vaccine efficacy in hamsters, showing reduced pulmonary immune activation and improved disease outcomes after prime-boost vaccination.

bioRxiv · Jan 25, 2021 · PreprintImmunology

Single nucleus multi-omics regulatory atlas of the murine pituitary

F. M. Ruf-Zamojski, Z. Zhang, M. Zamojski, G. R. Smith, N. Mendelev, H. Liu, G. Nudelman, M. Moriwaki, H. Pincas, R. Gomez Castanon, V. D. Nair, N. Seenarine, M. A. S. Amper, X. Zhou, L. Ongaro, , S. C. Sealfon

The paper creates a single nucleus multi-omics atlas of the murine pituitary, revealing cell type-specific regulatory mechanisms and identifying a cis-regulatory region linked to fertility.

bioRxiv · Jun 6, 2020 · PreprintCell Biology