Author

S. D. Gilk

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 5 Organism:human· 3 Organism:mouse· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Assay:imaging· 1

Frequent Co-Authors

A. Sadi· 3 shared T. M. Clemente· 3 shared R. K. Angara· 2 shared A. Bienvenu· 1 shared A. Justis· 1 shared B. Bordignon· 1 shared C. Cazevieille· 1 shared C. Dupont· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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3 shared papersMicrobiology

A. Sadi

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

The multifunction Coxiella effector Vice stimulates macropinocytosis and interferes with the ESCRT machinery

A. Bienvenu, M. Burette, F. Cantet, M. Gourdelier, J. M. Swain, C. Cazevieille, T. Clemente, A. Sadi, C. Dupont, M. Le Fe, N. Bonetto, B. Bordignon, D. MURIAUX, S. D. Gilk, M. Bonazzi, E. Martinez

This study identifies the Coxiella effector Vice as a protein that manipulates host cell lipid composition and cellular pathways to form the Coxiella-containing vacuole.

bioRxiv · Mar 13, 2024 · PreprintMicrobiology

The novel bacterial effector protein CbEPF1 mediates ER-LD membrane contacts to regulate host lipid droplet metabolism

R. K. Angara, A. Sadi, S. D. Gilk

bioRxiv · Dec 11, 2023 · PreprintCell Biology

Coxiella burnetii deubiquitinates host TRAF6 to modulate the macrophage innate immune response

A. Sadi, T. M. Clemente, L. Augusto, R. K. Angara, S. D. Gilk

This paper shows Coxiella burnetii evades macrophage immunity by deubiquitinating TRAF6, disrupting IL-17 signaling and reducing antimicrobial responses.

bioRxiv · Mar 15, 2023 · PreprintMicrobiology

Coxiella burnetii Type 4B Secretion System-dependent manipulation of endolysosomal maturation is required for bacterial growth

S. D. Gilk, D. Samanta, T. M. Clemente

This study shows that Coxiella burnetii uses its Type 4B Secretion System to block endosomal acidification, preventing lysosome fusion and maintaining a less acidic vacuole that supports bacterial growth.

bioRxiv · May 21, 2019Microbiology

Coxiella burnetii blocks intracellular IL-17 signaling in macrophages

T. M. Clemente, M. Mulye, A. Justis, S. Nallandhighal, T. M. Tran, S. D. Gilk

This study identifies that Coxiella burnetii uses its T4BSS to downregulate IL-17 signaling in macrophages, enhancing bacterial survival.

bioRxiv · Jul 12, 2018Microbiology