Author

T. M. Tran

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 2 Plant Biology· 2 Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 4 Assay:bulk RNA-seq· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Organism:mouse· 2

Frequent Co-Authors

J. Huang· 2 shared A. Ahmed· 1 shared A. B. Coley· 1 shared A. B. Heimberger· 1 shared A. Goldman· 1 shared A. J. Kegler· 1 shared A. Justis· 1 shared A. K. Jaiswal· 1 shared

Activity by Year

2018-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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2 shared papersMicrobiology

J. Huang

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Immune Contexture of Isocitrate Dehydrogenase stratified Human Gliomas

P. Gupta, M. Dang, S. Oberai, M. M. Peshoff, N. Milam, A. Ahmed, K. Bojja, T. M. Tran, K. Cox, H. Shehwana, C. K. Matsuoka, J. Li, J. Gumin, A. Goldman, S. A. Seth, , K. P. Bhat

The paper provides a comprehensive analysis of immune contexture in IDH stratified human gliomas using single-cell RNA sequencing and spectral cytometry, identifying TREM2 as a novel immunotherapy target.

bioRxiv · Nov 8, 2022Immunology

Salmonella Outer Membrane Vesicles contain tRNA Fragments (tRFs) that Inhibit Bacteriophage P22 infection

D. Houserova, Y. Huang, M. V. Kasukurthi, B. C. Watters, F. F. Khan, R. V. Mehta, N. Y. Chaudhary, J. T. Roberts, J. D. DeMeis, T. K. Hobbs, K. R. Ghee, C. H. McInnis, N. P. Johns, A. J. Kegler, A. B. Coley, , G. M. Borchert

This study identifies tRNA fragments (tRFs) in Salmonella OMVs that inhibit bacteriophage P22 infection, showing their role in antiviral defense.

bioRxiv · Nov 9, 2021 · PreprintMicrobiology

Post-transcriptional gene regulation by the RNA binding protein IGF2BP3 is critical for MLL-AF4 mediated leukemogenesis

T. M. Tran, J. Philipp, J. Bassi, N. Nibber, J. Draper, T. Lin, J. K. Palanichamy, A. K. Jaiswal, O. Silva, M. Paing, J. King, S. Katzman, J. R. Sanford, D. S. Rao

This study identifies IGF2BP3 as a critical regulator of MLL-AF4-driven leukemogenesis, showing its role in enhancing disease progression and identifying it as a potential therapeutic target.

bioRxiv · Dec 20, 2020 · PreprintCancer Biology

The bacterial quorum sensing signal DSF hijacks Arabidopsis thaliana sterol biosynthesis to suppress plant innate immunity

T. M. Tran, Z. Ma, A. Triebl, S. Nath, Y. Cheng, B.-Q. Gong, X. Han, J. Wang, J.-F. Li, M. R. Wenk, F. Torta, S. Mayor, L. Yang, Y. MIAO

This study shows that the bacterial QS molecule DSF suppresses Arabidopsis innate immunity by altering sterol biosynthesis and disrupting FLS2 receptor dynamics.

Life Science Alliance · Aug 11, 2020Peer-reviewedPlant Biology

Longitudinal analysis of naturally acquired antibodies to PfEMP1 CIDR domain variants and their association with malaria protection

N. Obeng-Adjei, D. B. Larremore, L. Turner, A. Ongoiba, S. Li, S. Doumbo, T. B. Yazew, K. Kayentao, L. H. Miller, B. Traore, S. K. Pierce, C. O. Buckee, T. Lavstsen, P. D. Crompton, T. M. Tran

The paper analyzes longitudinal antibody responses to PfEMP1 CIDR domain variants and links specific IgG acquisitions to reduced risk of febrile malaria.

bioRxiv · Feb 11, 2020Immunology

qKW9 encodes a pentatricopeptide repeat protein affecting photosynthesis and grain filling in maize

J. Yan, J. Huang, G. Lu, L. Liu, M. S. Raihan, J. Xu, L. Jian, L. Zhao, T. M. Tran, Q. Zhang, J. Liu, W. Li, C. Wei, D. M. Braun, Q. Li, , D. Jackson

This study identifies qKW9, a gene affecting maize kernel weight by regulating photosynthesis through C-to-U editing of NdhB.

bioRxiv · Nov 20, 2019 · PreprintPlant Biology

Coxiella burnetii blocks intracellular IL-17 signaling in macrophages

T. M. Clemente, M. Mulye, A. Justis, S. Nallandhighal, T. M. Tran, S. D. Gilk

This study identifies that Coxiella burnetii uses its T4BSS to downregulate IL-17 signaling in macrophages, enhancing bacterial survival.

bioRxiv · Jul 12, 2018Microbiology

Robotic automation of droplet microfluidics

T. M. Tran, S. C. Kim, A. R. Abate

This paper demonstrates robotically-automated droplet microfluidics to streamline complex workflows, enhancing reliability and convenience through commercial fluid-handling robots.

bioRxiv · Mar 7, 2018Bioengineering