Group B streptococcal membrane vesicles induce proinflammatory cytokine production and are sensed in an NLRP3 inflammasome-dependent mechanism in human macrophages
C. R. McCutcheon, J. Gaddy, D. M. Aronoff, S. D. Manning, M. G. Petroff
This study shows that GBS membrane vesicles induce proinflammatory cytokines in macrophages via NLRP3 inflammasome-dependent mechanisms, suggesting potential for immunotherapeutic targeting.
bioRxiv · Aug 10, 2022 · PreprintImmunology