ImmunologybioRxiv
Immunomodulatory effects of cytokine-induced expansion of cytotoxic lymphocytes in a mouse model of lupus-like disease
S. D. Reighard, D. Krishnamurthy, H. Cevik…·S. N. Waggoner
This study shows that expanding cytotoxic lymphocytes with IL-2 and IL-15 worsens lupus-like disease in mice, likely due to CD8 T cell expansion rather than NK cells.
DOI 10.1016/j.jcyt.2020.09.003