Author

s. Darnell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:proteomics· 2

Frequent Co-Authors

A. Begum· 1 shared A. E. Jerse· 1 shared A. E. Sikora· 1 shared A. Jerse· 1 shared A. Le Van· 1 shared A. N. Macintyre· 1 shared B. I. Baarda· 1 shared C. Gomez· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

A. Begum

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2 papers

Recent·Most cited

The serogroup B meningococcal outer membrane vesicle-based vaccine 4CMenB induces cross-species protection against Neisseria gonorrhoeae

I. Leduc, K. L. Connolly, A. Begum, K. Underwood, N. Rahman, s. Darnell, J. Balthazar, w. shafer, A. N. Macintyre, g. sempowski, A. Jerse

This paper demonstrates that the 4CMenB vaccine, based on Neisseria meningitidis outer membrane vesicles, provides cross-species protection against Neisseria gonorrhoeae in a mouse model, with antibodies targeting several surface proteins.

PLOS Pathogens · Dec 8, 2020Peer-reviewedMicrobiology

A novel gonorrhea vaccine composed of MetQ lipoprotein formulated with CpG shortens experimental murine infection

A. E. Sikora, C. Gomez, A. Le Van, B. I. Baarda, s. Darnell, F. G. Martinez, R. A. Zielke, J. A. Bonventre, A. E. Jerse

This study evaluates a gonorrhea vaccine candidate, rMetQ-CpG, showing it induces protective immune responses and accelerates bacterial clearance in a murine model.

bioRxiv · Jun 19, 2020Microbiology