The serogroup B meningococcal outer membrane vesicle-based vaccine 4CMenB induces cross-species protection against Neisseria gonorrhoeae
I. Leduc, K. L. Connolly, A. Begum, K. Underwood, N. Rahman, s. Darnell, J. Balthazar, w. shafer, A. N. Macintyre, g. sempowski, A. Jerse
This paper demonstrates that the 4CMenB vaccine, based on Neisseria meningitidis outer membrane vesicles, provides cross-species protection against Neisseria gonorrhoeae in a mouse model, with antibodies targeting several surface proteins.
PLOS Pathogens · Dec 8, 2020Peer-reviewedMicrobiology