K. L. Connolly

Evaluating vaccine-elicited antibody activities against Neisseria gonorrhoeae: cross-protective responses elicited by the 4CMenB meningococcal vaccine

This study evaluates antibody activities against Neisseria gonorrhoeae using assays to assess vaccine efficacy, showing cross-protective responses from the 4CMenB meningococcal vaccine.

A novel oral GyrB/ParE dual binding inhibitor effective against multidrug resistant Neisseria gonorrhoeae and other high-threat pathogens

The paper describes a novel oral inhibitor, JSF-2659, effective against multidrug-resistant Neisseria gonorrhoeae and other high-threat pathogens, with low potential for resistance development.

The serogroup B meningococcal outer membrane vesicle-based vaccine 4CMenB induces cross-species protection against Neisseria gonorrhoeae

This paper demonstrates that the 4CMenB vaccine, based on Neisseria meningitidis outer membrane vesicles, provides cross-species protection against Neisseria gonorrhoeae in a mouse model, with antibodies targeting several surface proteins.

Ribosome rescue inhibitors clear Neisseria gonorrhoeae in vivo using a new mechanism

The paper describes the development of ribosome rescue inhibitors that clear drug-resistant Neisseria gonorrhoeae in vivo through a novel mechanism involving ribosomal conformational changes.