Requirement for specific bacterial genome maintenance pathways in repair of C8-linked pyrrolobenzodiazepine (PBD) bi-aryl monomer-mediated DNA damage
A. Joseph, K. Nahar, S. Daw, M. Hasan, R. Lo, T. B. K. Le, K. Rahman, A. Badrinarayanan
This study investigates how C8-linked PBD bi-aryl monomers cause DNA damage in Caulobacter crescentus and identifies the repair mechanisms required for survival.
bioRxiv · Jun 10, 2022 · PreprintMicrobiology