Author

S. Deindl

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Assay:fluorescence / live-cell microscopy· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

A. Sabantsev· 2 shared E. Marklund· 2 shared G. Mao· 2 shared J. Elf· 2 shared L. Lehmann· 2 shared A. Emmerich· 1 shared B. van Oosten· 1 shared D. Dimakou· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersBiophysics

A. Sabantsev

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Author profile →

3 papers

Recent·Most cited

Structure and dynamics of the chromatin remodeler ALC1 bound to a PARylated nucleosome

L. Bacic, G. Gaullier, A. Sabantsev, L. Lehmann, K. Brackmann, D. Dimakou, M. Halic, G. Hewitt, S. J. Boulton, S. Deindl

This study determines the structure of ALC1 bound to a PARylated nucleosome using cryo-EM, revealing intermediate states and functional roles in nucleosome remodeling.

bioRxiv · Jun 18, 2021Biophysics

Sequence specificity in DNA binding is determined by association rather than dissociation

E. Marklund, G. Mao, S. Deindl, J. Elf

The paper derives an equation linking association and dissociation rates in DNA-protein binding and tests it using LacI and dCas9, showing sequence specificity is determined by recognition efficiency, not dissociation rates.

bioRxiv · Apr 8, 2021 · PreprintBiophysics

Mechanism of DNA surface exploration and operator bypassing during target search

E. Marklund, B. van Oosten, G. Mao, E. Amselem, K. Kipper, A. Sabantsev, A. Emmerich, D. Globisch, X. Zhen, L. Lehmann, O. Berg, M. Johansson, J. Elf, S. Deindl

This study uses SMCT-FCS to show LacI slides on DNA, bypassing target sequences by hopping out of the DNA groove, revealing a speed-accuracy trade-off in target search.

bioRxiv · Jan 29, 2020Biophysics