Author

X. Zhen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 2 Microbiology· 2 Plant Biology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 3 Assay:proteomics· 3 Approach:statistical model· 3 Organism:bacteria (other)· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Organism:human· 2

Frequent Co-Authors

Y. Chen· 3 shared G. Yan· 2 shared H. Sun· 2 shared J. Liu· 2 shared L. Ding· 2 shared L. Wang· 2 shared T. Zhang· 2 shared X. Tang· 2 shared

Activity by Year

2020-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersCancer Biology

Y. Chen

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

O-Glycosylated RNA Identification and Site-specific Prediction by Solid-phase Chemoenzymatic TnORNA method and PONglyRNA tool

J. Li, L. Wang, Y. Chen, S. Zhang, Z. Wen, X. Zhen, H. Zhang, Y. Zhou, S. Yang

This paper identifies and predicts O-glycosylated RNA using a chemoenzymatic method and a computational tool, revealing their role in pancreatic cancer progression.

bioRxiv · Jun 18, 2024 · PreprintCancer Biology

PRMT5 deficiency disturbs Nur77 methylation to inhibit endometrial stromal cell differentiation in recurrent implantation failure

Z. Cao, X. Wang, Y. Liu, X. Tang, M. Wu, X. Zhen, N. Kang, L. Ding, J. Sun, X. Cai, H. Sun, G. Yan, R. JIANG

This study shows PRMT5 deficiency disrupts Nur77 methylation, impairing endometrial stromal cell differentiation and contributing to recurrent implantation failure.

bioRxiv · Feb 6, 2024 · PreprintCell Biology

Structural insights into specific recognition of PTENα/β-NTE by WDR5 in cancer progression

X. Huang, C. Zhang, X. Shang, Y. Chen, Q. Xiao, Z. Wei, G. Wang, X. Zhen, G. Xu, J. Min, S. Shen, Y. Liu

The paper determines the crystal structure of PTEN-NTE bound to WDR5, revealing a specific binding motif that promotes tumor growth and suggests WDR5 inhibitors as potential cancer therapies.

bioRxiv · Dec 9, 2023 · PreprintCancer Biology

A novel bacterial signal transduction system specifically senses and responds to peptidoglycan damage

J. Yin, C. Xu, X. Hu, T. Zhang, Y. Liang, Y. Sun, X. Zhen, Y. Zhu, Y. Luo, P. Shen, D. Cheng, Y. Sun, J. Cai, Q. Meng, T. Zhu, , Z. Yu

This study identifies a bacterial two-component system that detects and responds to peptidoglycan damage, revealing its role in antibiotic resistance and tolerance.

bioRxiv · May 5, 2023 · PreprintMicrobiology

Sequential functional differentiation of luminal epithelial cells regulated by maternal and embryonic signaling in the mouse endometrium

H. Wang, D. Li, J. Liu, Y. Jiang, J. Zhou, Z. Wang, X. Tang, Y. Zhang, X. Zhen, Z. Cao, X. Sheng, C. Yang, Q. Yue, L. Ding, Y. Hu, , H. Sun

The paper identifies maternal and embryonic signaling-driven differentiation of luminal epithelial cells in the mouse endometrium and shows conservation in humans.

bioRxiv · Apr 30, 2022 · PreprintCell Biology

Engineering bacterial blight-resistant plants through CRISPR/Cas9-targeted editing of the MeSWEET10a promoter in cassava

Y. Wang, M. Geng, R. Pan, T. Zhang, X. Lu, X. Zhen, Y. Che, R. Li, J. Liu, Y. Chen, J. Guo, Y. Yao

This study edits the MeSWEET10a promoter in cassava to confer resistance to bacterial blight without affecting yield traits.

bioRxiv · Mar 2, 2022 · PreprintPlant Biology

Pan-genome analyses of peach and its wild relatives provide insights into the genetics of disease resistance and species adaptation

K. Cao, Z. Peng, X. Zhen, Y. Li, K. Liu, P. Arus, G. Zhu, S. Deng, W. Fang, C. Chen, X. Wang, J. Wu, Z. Fei, L. Wang

The paper performs pan-genome analysis of peach and its wild relatives to identify genetic variations related to disease resistance and high-altitude adaptation.

bioRxiv · Jul 13, 2020Plant Biology

Interplay between bacterial deubiquitinase and ubiquitin E3 ligase regulates ubiquitin dynamics on Legionella phagosomes

Z.-Q. Luo, S. Liu, J. Luo, X. Zhen, J. Qiu, S. Ouyang

The paper identifies Lem27 as a bacterial deubiquitinase that regulates ubiquitin dynamics on Legionella phagosomes by counteracting E3 ligases.

bioRxiv · May 19, 2020Microbiology

Mechanism of DNA surface exploration and operator bypassing during target search

E. Marklund, B. van Oosten, G. Mao, E. Amselem, K. Kipper, A. Sabantsev, A. Emmerich, D. Globisch, X. Zhen, L. Lehmann, O. Berg, M. Johansson, J. Elf, S. Deindl

This study uses SMCT-FCS to show LacI slides on DNA, bypassing target sequences by hopping out of the DNA groove, revealing a speed-accuracy trade-off in target search.

bioRxiv · Jan 29, 2020Biophysics