Author

S. Denham

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Physiology· 2 Pathology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Organism:human· 1

Frequent Co-Authors

A. Boyle· 1 shared A. Czopek· 1 shared A. J. Malbon· 1 shared A. M. Beekman· 1 shared A. Taddei· 1 shared A. Tchernof· 1 shared A. W. Horne· 1 shared B. Higgins· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperPhysiology

A. Boyle

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Carbonyl Reductase 1: a novel regulator of blood pressure in Down Syndrome

A. J. Malbon, A. Czopek, A. M. Beekman, Z. R. Goddard, A. Boyle, J. Ivy, K. Stewart, S. Denham, J. P. Simpson, N. Z. Homer, B. R. Walker, N. Dhaun, M. A. Bailey, R. Morgan

This study identifies CBR1 as a regulator of blood pressure in Down Syndrome, showing that its inhibition can increase blood pressure in a DS mouse model.

bioRxiv · May 17, 2024Physiology

Kynurenine monooxygenase blockade reduces endometriosis-like lesions, improves visceral hyperalgesia, and rescues mice from a negative behavioural phenotype in experimental endometriosis.

B. Higgins, I. Simitsidellis, X. Zheng, F. Collins, N. Homer, S. Denham, J. Simpson, M. Millar, L. Boswell, H. Y. Lee, Y. G. Kim, K. H. Park, L. C. Park, P. J. Sweeney, G. Feraille, , D. J. Mole

This study shows that blocking Kynurenine monooxygenase (KMO) reduces endometriosis-like lesions, alleviates pain, and improves behavior in a mouse model of endometriosis.

bioRxiv · May 13, 2024 · PreprintPathology

Increased adipose tissue indices of androgen catabolism and aromatization in women with metabolic dysfunction

G. Ostinelli, S. Laforest, S. Denham, M.-F. Gauthier, V. D. Labelle, E. Scott, F. S. Hould, S. Marceau, N. Z. M. Homer, C. Begin, R. Andrew, A. Tchernof

The paper investigates associations between intra-adipose steroid concentrations, steroidogenic enzyme activity, and adipose tissue dysfunction in women with severe obesity.

bioRxiv · Apr 4, 2022Physiology