Author

R. Morgan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Immunology· 2 Microbiology· 2 Physiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Assay:bulk RNA-seq· 4 Research Focus:cell type annotation· 4 Research Focus:host-pathogen & immune response· 4 Research Focus:drug response / drug discovery· 3 Organism:human· 3 Research Focus:differential expression· 2 Organism:mouse· 2

Frequent Co-Authors

A. G. Kay· 2 shared B. Barnes· 2 shared F. Jutfelt· 2 shared J. McGrail· 2 shared L. Nelson· 2 shared M. Hyland· 2 shared N. R. Forsyth· 2 shared O. Kehoe· 2 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersImmunology

A. G. Kay

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

A genome-wide cytotoxicity screen of Cluster F1 mycobacteriophage Girr reveals novel inhibitors of Mycobacterium smegmatis growth

R. S. Pollenz, K. Barhnhill, A. Biggs, J. Bland, V. Carter, M. Chase, H. Clark, C. Coleman, M. Daffner, C. Deam, A. Finocchiaro, V. Franco, T. Fuller, J. G. Pinera, M. Horne, , D. Heller

This study screens phage genes to identify inhibitors of Mycobacterium smegmatis growth, finding 29 toxic genes, 12 of which are novel antimicrobial proteins.

bioRxiv · Aug 4, 2023 · PreprintMicrobiology

A yeast-based system to study SARS-CoV-2 Mpro structure and to identify nirmatrelvir resistant mutations

J. Ou, E. Lewandowski, Y. Hu, A. Lipinski, R. Morgan, L. Jacobs, X. Zhang, M. Bikowitz, P. Langlais, H. Tan, J. Wang, Y. Chen, J. S. Choy

This study uses a yeast-based system to identify nirmatrelvir-resistant mutations in SARS-CoV-2 Mpro and confirms findings with structural analysis.

bioRxiv · Aug 6, 2022 · PreprintMicrobiology

Water salinity does not affect acute thermal tolerance (CTmax) in zebrafish (Danio rerio)

E. R. Asheim, A. H. Andreassen, R. Morgan, M. Silvestre, F. Jutfelt

This study finds that water salinity does not affect acute thermal tolerance in zebrafish after short or long exposure, but notes unexpected behavior in high salinity conditions.

bioRxiv · Aug 2, 2022 · PreprintPhysiology

Vitamin D receptor cistrome-transcriptome analyses establishes quantitatively distinct receptor genomic interactions in African American prostate cancer regulated by BAZ1A

M. Siddappa, S. Hussain, S. A. Wani, H. Tang, H. Jafari, J. S. Gray, M. D. Long, I. Elhussin, B. Karanam, H. Wang, R. Morgan, G. Hardiman, I. B. Adelani, S. Rotimi, A. R. Murphy, , M. J. Campbell

The paper analyzes VDR genomic interactions in African American prostate cancer cells and identifies BAZ1A as a regulator of VDR-dependent transcriptional responses.

bioRxiv · Jan 31, 2022 · PreprintCancer Biology

THERAPEUTIC EFFECTS OF HYPOXIC AND PRO-INFLAMMATORY PRIMING OF MESENCHYMAL STEM CELL-DERIVED EXTRACELLULAR VESICLES IN INFLAMMATORY ARTHRITIS

A. G. Kay, K. Treadwell, P. Roach, R. Morgan, R. Lodge, M. Hyland, A. Piccinini, N. R. Forsyth, O. Kehoe

This study evaluates the therapeutic effects of hypoxically and pro-inflammatory primed MSC-derived EVs in inflammatory arthritis, finding normoxic EVs most effective in reducing joint swelling and improving histopathology.

bioRxiv · Jun 28, 2021Immunology

Classification of ovarian cancer cell lines using transcriptional profiles defines the five major pathological subtypes

B. Barnes, L. Nelson, A. Tighe, R. Morgan, J. McGrail, S. S. Taylor

This paper classifies ovarian cancer cell lines into five subtypes using transcriptional profiles, aligning with known pathological subtypes and providing a method for future classification.

bioRxiv · Jul 14, 2020 · PreprintCancer Biology

PARG inhibition induces replication catastrophe in ovarian cancer cells with down-regulated DNA replication genes

C. Coulson-Gilmer, R. Morgan, L. Nelson, B. Barnes, J. McGrail, S. Taylor

This study shows that PARG inhibition causes replication catastrophe in some ovarian cancer cells with down-regulated DNA replication genes, suggesting a potential biomarker for PARG inhibitor response.

bioRxiv · Jul 13, 2020 · PreprintCancer Biology

MSCs from syndecan-3 null mice exhibit enhanced adhesion to collagen type I, hyperactivation of the AKT pathway and increased efficacy in inflammatory arthritis

F. K. Jones, A. Stefan, A. G. Kay, M. Hyland, R. Morgan, N. R. Forsyth, A. Pisconti, O. Kehoe

This study shows that SDC3-deficient MSCs adhere better to collagen I, have hyperactive AKT signaling, and are more effective in treating inflammatory arthritis.

bioRxiv · Jun 12, 2020Immunology

Brain cooling marginally increases maximum thermal tolerance in Atlantic cod

F. Jutfelt, D. Roche, T. D. Clark, T. Norin, S. Binning, B. Speers-Roesch, M. Amcoff, R. Morgan, A. Andreassen, J. Sundin

The study tests if brain cooling increases thermal tolerance in Atlantic cod, finding a small increase in critical thermal maximum.

bioRxiv · Jun 3, 2019Physiology