Author

S. Diecke

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Assay:ATAC-seq· 1 Research Focus:clustering· 1

Frequent Co-Authors

S. Frahm· 2 shared A. B. Tobin· 1 shared A. Heinz· 1 shared A. J. Thrasher· 1 shared A. K. Amaya· 1 shared A. L. McCorkindale· 1 shared A. Prigione· 1 shared A. R. Taddei· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersBioengineering

S. Frahm

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Assessment of pre-clinical liver models based on their ability to predict the liver-tropism of AAV vectors

A. Westhaus, M. Cabanes-Creus, K. L. Dilworth, E. Zhu, D. Salas Gomez, R. G. Navarro, A. K. Amaya, S. Scott, M. Kwiatek, A. L. McCorkindale, T. E. Hayman, S. Frahm, D. P. Perocheau, B. M. Tran, E. Vincan, , L. Lisowski

This study evaluates six AAV vectors in twelve preclinical liver models to identify the most predictive for AAV capsid selection in human hepatocyte transgene delivery.

bioRxiv · Sep 28, 2022 · PreprintBioengineering

Induced pluripotent stem cells and cerebral organoids from the critically endangered Sumatran rhinoceros

V. Zywitza, S. Frahm, N. Krueger, A. Weise, F. Goeritz, R. Hermes, S. Holtze, S. Colleoni, C. Galli, M. Drukker, T. B. Hildebrandt, S. Diecke

The paper generates and characterizes induced pluripotent stem cells (iPSCs) from the Sumatran rhinoceros to aid in conservation efforts.

bioRxiv · May 12, 2022Cell Biology

One gene - two proteins: The C-terminus of the prototypical M2 muscarinic receptor localizes to the mitochondria and regulates cell respiration.

F. Petragnano, I. Fasciani, Z. Wang, R. Edwards, N. Telugu, I. Pietrantoni, U. Zabel, H. Zauber, M. Grieben, M. E. Terzenidou, J. Di Gregorio, C. Pellegrini, S. Santini, A. R. Taddei, B. Poehl, , R. Maggio

The paper shows that the C-terminal fragment of the M2 muscarinic receptor localizes to mitochondria and regulates cell respiration, independent of its canonical GPCR function.

bioRxiv · Apr 13, 2021Cell Biology

Assessment of ethanol-induced toxicity on iPSC-derived human dopaminergic neurons using a novel high-throughput mitochondrial neuronal health (MNH) assay

A. Zink, J. Conrad, N. S. Telugu, S. Diecke, A. Heinz, E. E. Wanker, J. Priller, A. Prigione

The paper develops a high-throughput MNH assay to assess ethanol-induced toxicity in human dopaminergic neurons and identifies potential modulating drugs.

bioRxiv · Aug 12, 2020Cell Biology