Recent thymic emigrants produce antimicrobial IL-8, express complement receptors and are precursors of a tissue-homing Th8 lineage of memory cells
M. L. Pekalski, A. Rubio Garcia, R. C. Ferreira, D. B. Rainbow, D. J. Smyth, M. Mashar, J. Brady, N. Savinykh, X. Castro Dopico, S. Mahmood, S. Duley, H. E. Stevens, N. M. Walker, A. J. Cutler, F. Waldron-Lynch, , L. S. Wicker
The paper identifies CR2+ naive T cells as recent thymic emigrants that express antimicrobial IL-8 and complement receptors, and may become tissue-homing memory cells.
bioRxiv · Jun 17, 2016Immunology