Author

A. J. Cutler

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:flow cytometry· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

J. A. Todd· 3 shared R. C. Ferreira· 3 shared C. Wallace· 2 shared D. B. Dunger· 2 shared D. B. Rainbow· 2 shared D. J. Smyth· 2 shared L. S. Wicker· 2 shared M. L. Pekalski· 2 shared

Activity by Year

2016-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

J. A. Todd

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Author profile →

4 papers

Recent·Most cited

Whole-genome sequencing of a sporadic primary immunodeficiency cohort

J. E. D. Thaventhiran, H. Lango Allen, O. S. Burren, W. Rae, D. Greene, E. Staples, Z. Zhang, J. H. R. Farmery, I. Simeoni, J. Maimaris, C. Penkett, J. Stephens, S. V. V. Deevi, A. Sanchis-Juan, N. S. Gleadall, , Kuma

This study uses whole-genome sequencing of a PID cohort to identify genetic mutations and associations, revealing both monogenic and common variant contributions to immune dysfunction.

bioRxiv · May 7, 2020Immunology

Discovery of CD80 and CD86 as recent activation markers on regulatory T cells by protein-RNA single-cell analysis

D. Trzupek, M. Dunstan, A. J. Cutler, M. Lee, L. Godfrey, D. Aschenbrenner, H. H. Uhlig, L. Wicker, J. A. Todd, R. C. Ferreira

The paper uses a hybrid transcriptomic and proteomic approach to identify CD80 and CD86 as markers of recently activated regulatory T cells in human CD4+ T cells.

bioRxiv · Nov 29, 2019Immunology

Cells With Treg-Specific FOXP3 Demethylation But Low CD25 Are Prevalent In Autoimmunity

R. C. Ferreira, H. Z. Simons, W. Thompson, D. B. Rainbow, X. Yang, A. J. Cutler, J. Oliveira, X. C. Dopico, D. J. Smyth, N. Savinykh, M. Mashar, T. Vyse, D. B. Dunger, H. Baxendale, A. Chandra, , M. L. Pekalski

The paper identifies CD25lowFOXP3+ T cells as a subset of regulatory T cells expanded in autoimmune diseases, characterized by FOXP3 demethylation and distinct functional features.

bioRxiv · May 5, 2017Immunology

Recent thymic emigrants produce antimicrobial IL-8, express complement receptors and are precursors of a tissue-homing Th8 lineage of memory cells

M. L. Pekalski, A. Rubio Garcia, R. C. Ferreira, D. B. Rainbow, D. J. Smyth, M. Mashar, J. Brady, N. Savinykh, X. Castro Dopico, S. Mahmood, S. Duley, H. E. Stevens, N. M. Walker, A. J. Cutler, F. Waldron-Lynch, , L. S. Wicker

The paper identifies CR2+ naive T cells as recent thymic emigrants that express antimicrobial IL-8 and complement receptors, and may become tissue-homing memory cells.

bioRxiv · Jun 17, 2016Immunology