A repurposed drug screen identifies compounds that inhibit the binding of the COVID-19 spike protein to ACE2
K. B. Tsegay, C. M. Adeyemi, E. P. Gniffke, D. N. E. P. Sather, J. K. Walker, S. E. P. Smith
The paper screens 2701 approved drugs to find those inhibiting SARS-CoV-2 spike protein binding to ACE2, identifying 56 compounds with >90% inhibition and modeling their docking.
bioRxiv · Apr 8, 2021Pharmacology & Toxicology