Author

S. E. Spencer Miko

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1

Frequent Co-Authors

G. B. Morin· 2 shared A. Babaian· 1 shared A. Liu· 1 shared A. Nagelberg· 1 shared C. Brandstadter· 1 shared D. Fansworth· 1 shared D. Girodat· 1 shared D. L. Mager· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

G. B. Morin

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJun 28, 2021

A novel small molecule that induces cytotoxicity in lung cancer cells inhibits disulfide reductases GSR and TXNRD1

F. D. Johnson, J. Ferrarone, A. Liu…·W. W. Lockwood

The paper identifies LCS3, a compound that induces oxidative stress in lung cancer cells by inhibiting disulfide reductases GSR and TXNRD1, and shows its synergistic effect with glutathione and thioredoxin pathway inhibition.

DOI 10.1101/2021.06.28.450088

humanproteomics

𝕏 PostBluesky

Cancer BiologybioRxivFeb 6, 2020

Loss of macp{Psi} ribosomal RNA modification is a major feature of cancer

A. Babaian, K. Rothe, D. Girodat…·D. L. Mager

The paper identifies a cancer-specific rRNA modification loss in multiple cancers, linking it to oncogenic translational signatures and potential therapeutic targets.

DOI 10.1016/j.celrep.2020.107611

humanbulk RNA-seq

𝕏 PostBluesky