New factors for protein transport identified by a genome-wide CRISPRi screen in mammalian cells
L. Bassaganyas, S. J. Popa, M. Horlbeck, A. Ashok, S. E. Stewart, C. M. Butnaru, N. Brouwers, K. Heydari, J. Ripoche, J. Weissman, R. Schekman, V. Malhotra, K. Moreau, J. Villeneuve
The paper identifies two new factors, TTC17 and CCDC157, involved in protein transport through a CRISPRi screen in mammalian cells, showing their roles in Golgi structure and transport carrier fusion.
bioRxiv · Feb 21, 2019Cell Biology