Author

S. F. Leiser

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 3

Signature Assays, Organisms & Methods

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Organism:C. elegans· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

S. Beydoun· 2 shared A. Bugarin-Lapuz· 1 shared A. Vaid· 1 shared C. Tran· 1 shared E. Chavez· 1 shared E. S. Kitto· 1 shared E. Wang· 1 shared J. Mecano· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersPhysiology

S. Beydoun

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Author profile →

3 papers

Recent·Most cited

Food touch limits lifespan through bioamine and neuroendocrine signaling.

E. S. Kitto, S. Beydoun, S. F. Leiser

This study shows that touch perception interacts with dietary restriction to modulate lifespan in C. elegans through bioamine and neuroendocrine signaling.

bioRxiv · Apr 19, 2024 · PreprintPhysiology

Fmo5 plays a sex-specific role in goblet cell maturation and mucus barrier formation

M. L. Schaller, M. M. Sykes, J. Mecano, S. Solanki, W. Huang, R. J. Rebernick, S. Beydoun, E. Wang, A. Bugarin-Lapuz, Y. M. Shah, S. F. Leiser

This study identifies Fmo5's sex-specific role in goblet cell maturation and mucus barrier formation in the intestine, with severe effects in female mice.

bioRxiv · Apr 5, 2024Physiology

Intermittent hypoxia therapy engages multiple longevity pathways to double lifespan in C.elegans

J. N. Pitt, E. Chavez, K. M. Provencher, M. Chen, C. Tran, J. Tran, K. Huang, A. Vaid, M. L. Abadir, N. Arang, S. F. Leiser, M. B. Roth, M. Kaeberlein

This study shows intermittent hypoxia therapy doubles C. elegans lifespan without HIF-1 but requires DAF-16/FOXO and other phosphatidylinositol signaling components.

bioRxiv · Oct 13, 2022 · PreprintPhysiology