Author

J. N. Pitt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:genetic perturbation / CRISPR· 2 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

M. Kaeberlein· 2 shared A. Kaya· 1 shared A. Mendenhall· 1 shared A. Tyshkovskiy· 1 shared A. Vaid· 1 shared B. W. Blue· 1 shared C. Tran· 1 shared E. Chavez· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersPhysiology

M. Kaeberlein

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Intermittent hypoxia therapy engages multiple longevity pathways to double lifespan in C.elegans

J. N. Pitt, E. Chavez, K. M. Provencher, M. Chen, C. Tran, J. Tran, K. Huang, A. Vaid, M. L. Abadir, N. Arang, S. F. Leiser, M. B. Roth, M. Kaeberlein

This study shows intermittent hypoxia therapy doubles C. elegans lifespan without HIF-1 but requires DAF-16/FOXO and other phosphatidylinositol signaling components.

bioRxiv · Oct 13, 2022 · PreprintPhysiology

Evidence that conserved essential genes are enriched for pro-longevity factors

N. Oz, E. Vayndorf, M. Tsuchiya, S. McLean, L. Turcios-Hernandez, J. N. Pitt, B. W. Blue, M. Muir, M. G. Kiflezghi, A. Tyshkovskiy, A. Mendenhall, M. Kaeberlein, A. Kaya

The paper shows that overexpressing conserved essential genes in yeast increases replicative lifespan more than deleting them, suggesting essential genes are important for longevity.

bioRxiv · Mar 18, 2022Cell Biology