Wnt-mediated interactions of tumor-initiating cells with a macrophage niche drive skin tumor formation
S. Fontenete, J. R. Christensen, A. Martinez-Silgado, E. Zarzuela, J. Munoz, D. Megias, D. Castellana, R. Loewe, M. Perez-Moreno
The paper identifies a macrophage-tumor-initiating cell niche regulated by Wnt signaling that drives skin tumor formation and maintenance.
bioRxiv · Jul 17, 2020 · PreprintCancer Biology