Author

S. G. Amin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:metabolomics· 2 Organism:mouse· 2 Assay:proteomics· 1

Frequent Co-Authors

K. Gowda· 3 shared A. Annalora· 2 shared A. D. Patterson· 2 shared C. Marcus· 2 shared F. Dong· 2 shared G. H. Perdew· 2 shared I. A. Murray· 2 shared D. Coslo· 1 shared

Activity by Year

2023-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersBiochemistry

K. Gowda

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3 papers

Recent·Most cited

A new efficacious Mcl-1 inhibitor maximizes bortezomib and venetoclax responsiveness in resistant multiple myeloma cells

O. S. F. Al Odat, K. Gowda, S. K. Srivastava, S. G. Amin, S. C. Jonnalagadda, T. Budak-Alpdogan, M. K. Pandey

This paper identifies KS18, a Mcl-1 inhibitor, as a potential treatment for multiple myeloma, showing it enhances apoptosis and overcomes resistance to bortezomib and venetoclax in resistant cells and mouse models.

bioRxiv · Dec 6, 2023 · PreprintPharmacology & Toxicology

Complex chemical signals dictate Ah receptor activation through the gut-lung axis

F. Dong, I. A. Murray, A. Annalora, D. Coslo, D. Desai, K. Gowda, J. Yang, D. Wang, I. Koo, F. Hao, S. G. Amin, A. D. Patterson, C. Marcus, G. H. Perdew

The paper shows that urolithin A enhances AHR activity in gut and lung tissues by reducing clearance via CYP1A1/1B1, suggesting a role for dietary substrates in modulating AHR signaling through the gut-lung axis.

bioRxiv · Feb 22, 2023Biochemistry

Contribution of circulating host and microbial tryptophan metabolites towards Ah receptor activation

E. W. Morgan, F. Dong, A. Annalora, I. A. Murray, T. Wolfe, R. Erickson, K. Gowda, S. G. Amin, K. S. Petersen, P. M. Kris-Etherton, C. Marcus, S. T. Walk, A. D. Patterson, G. H. Perdew

This study identifies host and microbial tryptophan metabolites in serum that activate the AHR, showing host production dominates in mice despite microbial sources.

bioRxiv · Jan 26, 2023Biochemistry