Author

S. G. Bhosle

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:CRISPR screen· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:perturbation response prediction· 1 Research Focus:variant effect prediction· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

E. Goncalves· 2 shared A. Barthorpe· 1 shared A. Beck· 1 shared A. R. Bassett· 1 shared C. Beaver· 1 shared C. Dincer· 1 shared C. Hall· 1 shared C. Hardy· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

E. Goncalves

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2 papers

Recent·Most cited

Base editing screens map mutations affecting IFNγ signalling in cancer

M. A. Coelho, E. Karakoc, S. G. Bhosle, E. Goncalves, T. Burgold, S. Cooper, C. M. Cattaneo, V. Veninga, S. Consonni, C. Dincer, S. F. Vieira, F. Gibson, S. Barthorpe, C. Hardy, J. Rein, , M. J. Garnett

This study uses base editing to identify mutations affecting IFNγ signalling in cancer, revealing loss- and gain-of-function variants with clinical relevance.

bioRxiv · Mar 29, 2022 · PreprintCancer Biology

A suspension technique for efficient large-scale cancer organoid culturing and perturbation screens

S. Price, S. G. Bhosle, E. Goncalves, X. Li, D. McClurg, A. Barthorpe, A. Beck, C. Hall, H. Lightfoot, L. Farrow, R. Ansari, D. A. Jackson, L. Allen, K. Roberts, C. Beaver, , M. Garnett

This paper introduces a suspension culture technique for cancer organoids that improves expansion efficiency and enables large-scale perturbation screens.

bioRxiv · Oct 23, 2021Cancer Biology