S. Price

A suspension technique for efficient large-scale cancer organoid culturing and perturbation screens

This paper introduces a suspension culture technique for cancer organoids that improves expansion efficiency and enables large-scale perturbation screens.

The secrets to domestic bliss - Partner fidelity and environmental filtering preserve stage-specific turtle ant gut symbioses for over 40 million years

Quantifying multivariate genotype-by-environment interactions, evolutionary potential and its context-dependence in natural populations of the water flea, Daphnia magna.

The paper quantifies multivariate genotype-by-environment interactions in Daphnia magna and finds context-dependent evolutionary potential for food vs. temperature responses.

Siderophore-mediated zinc acquisition enhances enterobacterial colonization of the inflamed gut.

This study shows that the probiotic E. coli Nissle 1917 uses yersiniabactin to acquire zinc in inflamed gut conditions, enhancing its colonization.

Genetic immunodeficiency and autoimmune disease reveal distinct roles of Hem1 in the WAVE2 and mTORC2 complexes

Hem1 loss-of-function mutations cause congenital immunodysregulation by disrupting WAVE2 and mTORC2 complexes, leading to immunodeficiency and immune hyperresponsiveness.