BiochemistrybioRxivPreprint
Cryo-EM analyses of wild-type and oncogenic KIT mutants reveal structural oncogenic plasticity and a novel Achilles heel for therapeutic intervention
S. G. Krimmer, N. Bertoletti, Y. Suzuki…·J. Schlessinger
This study uses cryo-EM to analyze wild-type and oncogenic KIT mutants, revealing structural changes and a potential therapeutic target in cancer.