Dimerization mechanism and structural features of human LI-cadherin
A. Yui, J. M. M. Caaveiro, D. Kuroda, M. Nakakido, S. Nagatoishi, S. Goda, T. Maruno, S. Uchiyama, K. Tsumoto
This study determines the crystal structure of LI-cadherin EC1-4 homodimer and shows its unique architecture and noncanonical calcium ion-free linker, revealing the mechanism of homodimerization essential for cell adhesion.
bioRxiv · Sep 18, 2020Biochemistry