Author

S. Gottumukkala

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

M. Pazgier· 2 shared S. Ding· 2 shared W. D. Tolbert· 2 shared A. E. Finzi· 1 shared A. Finzi· 1 shared A. P. Hederman· 1 shared D. N. Nguyen· 1 shared D. Nguyen· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersMicrobiology

M. Pazgier

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2 papers

Recent·Most cited

Engineered ACE2-Fc counters murine lethal SARS-CoV-2 infection through direct neutralization and Fc-effector activities

Y. Chen, L. Sun, I. Ullah, G. Beaudoin-Bussieres, S. P. Anand, A. P. Hederman, W. D. Tolbert, R. Sherburn, D. N. Nguyen, L. Marchitto, S. Ding, D. Wu, Y. Luo, S. Gottumukkala, S. Moran, , M. Pazgier

The paper develops ACE2-Fc molecules that neutralize SARS-CoV-2 and show Fc-effector activity, effectively treating lethal infection in mice.

bioRxiv · Nov 24, 2021Microbiology

Across functional boundaries: making non-neutralizing antibodies to neutralize HIV-1 and mediate Fc-mediated effector killing of infected cells

J. Richard, D. Nguyen, W. D. Tolbert, R. Gasser, s. ding, D. Vezina, S. Yu Gong, J. Prevost, G. Gendron-Lepage, H. Medjahed, S. Gottumukkala, A. Finzi, M. Pazgier

This paper designs Ab-CD4 chimeric proteins that open HIV-1 Env trimers to expose non-neutralizing epitopes, enabling both neutralization and ADCC against HIV-1.

bioRxiv · Aug 13, 2021Immunology