Author

K. E. Pauken

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 4 Research Focus:differential expression· 3 Organism:human· 3 Assay:CITE-seq· 2 Approach:deep learning· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:scRNA-seq· 2

Frequent Co-Authors

K. A. Lagattuta· 2 shared O. Shahid· 2 shared A. Dahal· 1 shared A. E. Kim· 1 shared A. H. Jonsson· 1 shared A. H. Sharpe· 1 shared A. I. Daud· 1 shared A. Jain· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

K. A. Lagattuta

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Neoantigen Cancer Vaccines and Different Immune Checkpoint Therapies Each Utilize Both Converging and Distinct Mechanisms that in Combination Enable Synergistic Therapeutic Efficacy

S. Keshari, A. S. Shavkunov, Q. Miao, A. Saha, C. D. Williams, A. M. Highsmith, J. E. Pineda, E. Alspach, K. Hu, K. E. Pauken, K. Chen, M. M. Gubin

This study compares neoantigen vaccines and immune checkpoint therapies, finding they use distinct and overlapping mechanisms, with combined use showing superior efficacy.

bioRxiv · Dec 20, 2023Immunology

Microenvironmental correlates of immune checkpoint inhibitor response in human melanoma brain metastases revealed by T cell receptor and single-cell RNA sequencing

C. A. Alvarez-Breckenridge, S. C. Markson, J. H. Stocking, N. Nayyar, M. Lastrapes, M. R. Strickland, A. E. Kim, M. de Sauvage, A. Dahal, J. M. Larson, J. L. Mora, A. W. Navia, B. M. Kuter, C. M. Gill, M. S. Bertalan, , Bra

bioRxiv · Aug 25, 2021Cancer Biology

Repertoire analyses reveal TCR sequence features that influence T cell fate

K. A. Lagattuta, J. B. Kang, A. Nathan, K. E. Pauken, A. H. Jonsson, D. A. Rao, K. Ishigaki, S. Raychaudhuri

The paper identifies TCR sequence features that influence T cell fate by analyzing TCR sequences from human cells and developing a scoring system for regulatory potential.

bioRxiv · Jun 23, 2021Immunology

Single-cell analyses identify circulating anti-tumor CD8 T cells and markers for their enrichment

K. E. Pauken, O. Shahid, K. A. Lagattuta, K. M. Mahuron, J. M. Luber, M. M. Lowe, L. Huang, C. Delaney, J. M. Long, M. E. Fung, K. Newcomer, K. K. Tsai, M. Chow, S. Guinn, J. R. Kuchroo, , M. Singer

The paper identifies circulating anti-tumor CD8 T cells using single-cell RNA sequencing and TCR sequencing, and develops marker panels for their detection in mice and melanoma patients.

bioRxiv · Sep 30, 2020Immunology