Author

S. H. Pennington

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A. Owen· 2 shared C. H. Caygill· 2 shared R. C. Lopeman· 2 shared A. Ardrey· 1 shared A. Breen· 1 shared A. Valentijn· 1 shared E. I. Patterson· 1 shared E. Kijack· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersPharmacology & Toxicology

A. Owen

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2 papers

Recent·Most cited

Lack of antiviral activity of probenecid in Vero E6 cells and Syrian golden hamsters: a need for better understanding of inter-lab differences in preclinical assays.

H. J. Box, S. H. Pennington, E. Kijack, L. Tatham, C. H. Caygill, R. C. Lopeman, L. N. Jeffreys, J. Herriott, J. Sharp, M. Neary, A. Valentijn, H. Pertinez, P. Curley, U. Arshad, R. K. Rajoli, , A. Owen

This paper investigates probenecid's antiviral activity against SARS-CoV-2 in Vero E6 cells and Syrian golden hamsters, finding no significant inhibition of viral replication or cytopathic effects.

bioRxiv · Mar 3, 2022 · PreprintPharmacology & Toxicology

Remdesivir-Ivermectin combination displays synergistic interaction with improved in vitro antiviral activity against SARS-CoV-2

L. Jeffreys, S. H. Pennington, J. Duggan, C. H. Caygill, R. C. Lopeman, A. Breen, J. Jinks, A. Ardrey, S. Donnellan, E. I. Patterson, G. I. Hughes, W. D. Hong, P. M. O'Neill, G. Aljayyoussi, A. Owen, , G. A. Biagini

This study shows that combining remdesivir and ivermectin enhances antiviral activity against SARS-CoV-2 in vitro.

bioRxiv · Dec 23, 2020Microbiology