Author

S. H. Y. Loh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:metabolomics· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

L. M. Martins· 2 shared A. E. H. Yek· 1 shared A. Huerta Uribe· 1 shared A. Sanz· 1 shared C. Graham· 1 shared C. Soleilhavoup· 1 shared F. Scialo· 1 shared I. Chung· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersPharmacology & Toxicology

L. M. Martins

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2 papers

Recent·Most cited

Pharmacology & ToxicologybioRxivApr 2, 2023

The antipsychotic medications aripiprazole, brexpiprazole and cariprazine are off-target respiratory chain complex I inhibitors

R. E. Hardy, I. Chung, Y. Yu…·K. R. Pryde

This study shows that antipsychotics aripiprazole, brexpiprazole, and cariprazine inhibit mitochondrial respiratory complex I, causing toxicity and movement disorders.

DOI 10.1186/s13062-023-00375-9

mouseDrosophila

𝕏 PostBluesky

PhysiologybioRxivPreprintAug 18, 2021

ROS signalling requires uninterrupted electron flow and is lost during ageing in flies

C. Graham, R. Stefanatos, A. E. H. Yek…·A. Sanz

The paper shows that ROS-RET signalling requires uninterrupted electron flow through the ETC and is lost during ageing in flies, leading to persistent mtROS production and reduced stress adaptation.

DOI 10.1101/2021.08.18.456795

Drosophilaexperimental assay

𝕏 PostBluesky