Author

L. M. Martins

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Pharmacology & Toxicology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Assay:proteomics· 3 Research Focus:differential expression· 2 Organism:Drosophila· 2 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

M. MacFarlane· 2 shared N. Morone· 2 shared S. H. Y. Loh· 2 shared A. Craxton· 1 shared A. E. H. Yek· 1 shared A. Huerta Uribe· 1 shared A. Sanz· 1 shared C. Graham· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersPharmacology & Toxicology

M. MacFarlane

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

The antipsychotic medications aripiprazole, brexpiprazole and cariprazine are off-target respiratory chain complex I inhibitors

R. E. Hardy, I. Chung, Y. Yu, S. H. Y. Loh, N. Morone, C. Soleilhavoup, M. Travaglio, R. Serreli, L. Panman, K. Cain, J. Hirst, L. M. Martins, M. MacFarlane, K. R. Pryde

This study shows that antipsychotics aripiprazole, brexpiprazole, and cariprazine inhibit mitochondrial respiratory complex I, causing toxicity and movement disorders.

bioRxiv · Apr 2, 2023Pharmacology & Toxicology

TAp73 regulates mitochondrial dynamics and multiciliated cell homeostasis through an OPA1 axis

N. Buckley, A. Craxton, X.-M. Sun, E. Panatta, L. Pinon, J. Llodra, N. Morone, I. Amelio, G. Melino, L. M. Martins, M. MacFarlane

This study identifies TAp73's role in regulating mitochondrial dynamics and multiciliated cell homeostasis through the OPA1 axis, linking it to COPD pathogenesis.

bioRxiv · Mar 23, 2023Cell Biology

"The anti-apoptotic effect of Lonomia obliqua hemolymph is associated with the mitochondria pathway"

R. Z. Mendonca, L. M. Martins

The paper shows that a protein from Lonomia obliqua hemolymph prolongs cell viability by preventing mitochondrial membrane permeabilization and cytochrome c release.

bioRxiv · Jun 2, 2022 · PreprintCell Biology

ROS signalling requires uninterrupted electron flow and is lost during ageing in flies

C. Graham, R. Stefanatos, A. E. H. Yek, R. V. Spriggs, S. H. Y. Loh, A. Huerta Uribe, T. Zhang, L. M. Martins, O. D. K. Maddocks, F. Scialo, A. Sanz

The paper shows that ROS-RET signalling requires uninterrupted electron flow through the ETC and is lost during ageing in flies, leading to persistent mtROS production and reduced stress adaptation.

bioRxiv · Aug 18, 2021 · PreprintPhysiology