Author

S. Halpain

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Organism:mouse· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Assay:electrophysiology· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

B. Calabrese· 2 shared P. Rangamani· 2 shared A. Y. Shih· 1 shared D. L. Schmitt· 1 shared D. Ohadi· 1 shared H. Alimohamadi· 1 shared H. N. Higgs· 1 shared J. Zhang· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersCell Biology

B. Calabrese

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

INF2-mediated actin filament reorganization confers intrinsic resilience to neuronal ischemic injury

B. Calabrese, S. Jones, Y. Yamaguchi-Shiraishi, M. J. Lingelbach, U. Manor, T. M. Svitkina, H. N. Higgs, A. Y. Shih, S. Halpain

This study shows that INF2-mediated actin reorganization in neurons protects against ischemic injury by counteracting swelling-induced cell death.

bioRxiv · Oct 1, 2021Cell Biology

Mechanical principles governing the shapes of dendritic spines

H. Alimohamadi, M. Bell, S. Halpain, P. Rangamani

This study uses a biophysical model to explore mechanical principles governing dendritic spine shapes and their stability through actin structures and force regimes.

bioRxiv · Sep 9, 2020Biophysics

Computational modeling reveals frequency modulation of calcium-cAMP/PKA pathway in dendritic spines

D. Ohadi, D. L. Schmitt, B. Calabrese, S. Halpain, J. Zhang, P. Rangamani

The paper models calcium-induced cAMP/PKA dynamics in dendritic spines, showing that the pathway filters high-frequency calcium inputs to respond only to lower frequencies.

bioRxiv · Aug 5, 2019Biophysics