Author

S. Holzer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:structural biology· 1

Frequent Co-Authors

I. R. Short· 1 shared L. Pellegrini· 1 shared M. Jenkyn-Bedford· 1 shared M. L. Kilkenny· 1 shared N. J. Rzechorzek· 1 shared

Activity by Year

2019-2019 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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1 shared paperBiochemistry

I. R. Short

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1 paper

Recent·Most cited

Structural basis for inhibition of human primase by arabinofuranosyl nucleoside analogues Fludarabine and Vidarabine

S. Holzer, N. J. Rzechorzek, I. R. Short, M. Jenkyn-Bedford, L. Pellegrini, M. L. Kilkenny

This study provides a structural basis for how Fludarabine and Vidarabine inhibit human primase, suggesting ways to improve their therapeutic efficacy and reduce toxicity.

bioRxiv · Apr 11, 2019Biochemistry