Author

S. J. Haggarty

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:imaging· 1 Assay:proteomics· 1

Frequent Co-Authors

M. C. Silva· 2 shared A. Stolz· 1 shared A. Ta· 1 shared A. Verhelle· 1 shared C. A. Cuoco· 1 shared C. C. Chou· 1 shared C. Cole· 1 shared C. Wulkop-Gil· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCell Biology

M. C. Silva

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2 papers

Recent·Most cited

An mTOR-independent Macroautophagy Activator Ameliorates Tauopathy and Prionopathy Neurodegeneration Phenotypes

L. Yoon, R. C. Botham, A. Verhelle, Y. Wu, C. Cole, E. P. Tan, L. A. Massey, P. Sanz-Martinez, C. C. Chou, J. Xu, L. P. Elia, K. Lee, S. R. Labra, G. M. Kline, Q. Xiao, , S. Encalada

The paper identifies CCT020312, an mTOR-independent autophagy activator, which reduces tauopathy and prionopathy neurodegeneration phenotypes by enhancing autophagy flux and clearing protein aggregates.

bioRxiv · Sep 29, 2022 · PreprintCell Biology

Exifone is a Potent HDAC1 Activator with Neuroprotective Activity in Human Neuronal Models of Neurodegeneration

D. Patnaik, P.-C. Pao, W.-N. Zhao, M. C. Silva, N. K. Hylton, P. S. Chindavong, L. Pan, L.-H. Tsai, S. J. Haggarty

This paper identifies exifone as a potent HDAC1 activator that provides neuroprotection in human neuronal models of neurodegeneration by enhancing deacetylase activity and reducing histone acetylation.

bioRxiv · Mar 2, 2020Biochemistry