Author

E. P. Tan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:proteomics· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Artigues· 2 shared C. Slawson· 2 shared A. Denson· 1 shared A. Stolz· 1 shared A. Ta· 1 shared A. Verhelle· 1 shared C. A. Cuoco· 1 shared C. C. Chou· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersCell Biology

A. Artigues

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Multi-Omics after O-GlcNAc Alteration Identifies Cellular Processes Working Synergistically to Promote Aneuploidy

S. Boyd, D. Robarts, K. Nguyen, M. Villar, I. Alghusen, M. Kotulkar, A. Denson, H. Fedoosyuk, N. Lee, S. A. Whelan, J. A. Hanover, W. Dias, E. P. Tan, S. McGreal, A. Artigues, , C. Slawson

The paper uses multi-omics analysis to show OGT regulates aneuploidy by fine-tuning multiple cellular pathways through O-GlcNAcylation.

bioRxiv · Apr 16, 2024 · PreprintCell Biology

An mTOR-independent Macroautophagy Activator Ameliorates Tauopathy and Prionopathy Neurodegeneration Phenotypes

L. Yoon, R. C. Botham, A. Verhelle, Y. Wu, C. Cole, E. P. Tan, L. A. Massey, P. Sanz-Martinez, C. C. Chou, J. Xu, L. P. Elia, K. Lee, S. R. Labra, G. M. Kline, Q. Xiao, , S. Encalada

The paper identifies CCT020312, an mTOR-independent autophagy activator, which reduces tauopathy and prionopathy neurodegeneration phenotypes by enhancing autophagy flux and clearing protein aggregates.

bioRxiv · Sep 29, 2022 · PreprintCell Biology

Elevated O-GlcNAcylation Enhances Pro-Inflammatory Th17 Function by Altering the Lipid Microenvironment

M. Machacek, Z. Zhang, E. P. Tan, J. Li, T. Li, M. T. Villar, A. Artigues, T. Lydic, C. Slawson, P. Fields

The paper shows that elevated O-GlcNAcylation in CD4+ T cells enhances Th17 function by altering the lipid microenvironment, increasing IL-17A production in obesity.

bioRxiv · Apr 20, 2018Immunology