S. J. Russo

Circulating senescent myeloid cells drive blood brain barrier breakdown and neurodegeneration

This study identifies circulating senescent myeloid cells as drivers of blood-brain barrier breakdown and neurodegeneration in LCH-ND.

A double-hit of social and economic stress in mice precipitates changes in decision-making strategies

This study shows that mice with prior social defeat stress exhibit altered decision-making strategies when faced with economic stress, impacting food security and subjective value prioritization.

Social stress induces autoimmune responses against the brain to promote stress susceptibility

This study links social stress to autoimmune responses against the brain, showing increased IgG antibodies correlate with depression-like behaviors in mice and humans.

Chronic social stress induces isolated deficits in reward anticipation on a neuroeconomic foraging task

This study shows that chronic social stress impairs reward anticipation in mice, but not other reward-related behaviors, and that this effect is influenced by recent reward history and environmental demands.

Patient-specific iPSCs carrying an SFTPC mutation reveal the intrinsic alveolar epithelial dysfunction at the inception of interstitial lung disease

This study uses patient-derived iPSCs with an SFTPC mutation to model early alveolar epithelial dysfunction in interstitial lung disease, revealing proteostasis, metabolic, and inflammatory changes.