Author

J. Le Berichel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:cell-cell communication· 1 Approach:deep learning· 1

Frequent Co-Authors

L. Troncoso· 2 shared M. Buckup· 2 shared M. D. Park· 2 shared M. Merad· 2 shared P. Hamon· 2 shared S. Gnjatic· 2 shared A. Baccarini· 1 shared A. Bektesevic· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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2 shared papersCell Biology

L. Troncoso

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Circulating senescent myeloid cells drive blood brain barrier breakdown and neurodegeneration

C. M. Wilk, F. Cathomas, O. Torok, J. Le Berichel, M. D. Park, G. R. Heaton, P. Hamon, L. Troncoso, B. P. Scull, D. Dangoor, A. Silvin, R. Fleischmann, M. Belabed, H. Lin, E. M. Taouli, , M. Merad

This study identifies circulating senescent myeloid cells as drivers of blood-brain barrier breakdown and neurodegeneration in LCH-ND.

bioRxiv · Oct 10, 2023Cell Biology

Intratumoral mregDC and CXCL13 T helper niches enable local differentiation of CD8 T cells following PD-1 blockade

A. Magen, P. Hamon, N. Fiaschi, L. Troncoso, E. Humblin, D. D'souza, T. Dawson, M. D. Park, J. Kim, S. Hamel, M. Buckup, C. Chang, A. Tabachnikova, H. Schwartz, N. Malissen, , Merad

The paper identifies intratumoral niches involving mregDC and CXCL13+ Th cells that support CD8 T cell differentiation following PD-1 blockade in HCC patients.

bioRxiv · Jun 22, 2022 · PreprintImmunology

Perturb-map enables CRISPR genomics with spatial resolution and identifies regulators of tumor immune composition

M. Dhainaut, S. A. Rose, G. Akturk, A. Wroblewska, E. Sook Park, S. R. Nielsen, M. Buckup, V. Roudko, L. Pia, J. Le Berichel, A. Bektesevic, B. H. Lee, A. Baccarini, N. Bhardwaj, A. H. Rahman, , B. D. Brown

Perturb-map enables spatial CRISPR screening in tumors, identifying genes that regulate immune composition by mapping gene knockouts and their effects on the tumor microenvironment.

bioRxiv · Jul 13, 2021 · PreprintImmunology